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Special Symposium "Nanotech Agenda 2020"

Jan. 27 (Wed.) 10:30-13:00
Venue : Main theater in the exhibition / Fee : Free

Expectations for DDS technologies and their future prospects
from the industrial viewpoint 10:30-11:00

菊池 寛 氏

Hiroshi Kikuchi
Executive Director, Chief Innovation Officer Group, Eisai

[ Abstract ]

DDS (drug delivery system) is a technology for the biodistribution control of the drug which has both pharmacological effect and toxicological effect simultaneously. There are a very significant number of DDS medicines already launched out in the world. It is not too much to say that DDS has established itself as one of the major tools for drug development. Each DDS technology has not only advantages but also limitations respectively based on its characteristics, so it is considered very important to understand individual DDS technology in detail for development of DDS medicines. In this symposium, the simple overview of the current DDS technologies will be performed, and the near-future DDS technologies in 2020 will be predicted.

[ Profile ]

He entered Daiichi Pharm. after graduating from Univ. of Tokyo in 1977 and moved to Eisai in 2007. He has served as a Prof. of Univ. of Tokyo (1992-), Kyushu Univ. (2007-), Kyoto Univ. (2014-) and many others. He is also Trustee of The Pharmaceutical Society of Japan (2014-) and other academic societies. He received The 1st Nagai Award, JSDDS (2001), The Award, APSTJ (2010), etc.

Future of Mammalian Synthetic Biology and Molecular Robotics 11:00-11:30
齊藤 博英 氏

Hirohide Saito
Professor, Center for iPS Cell Research and Application (CiRA), Kyoto University

[ Abstract ]

Synthetic biology and nanobiotechnology have a promising outlook in biological research and future therapeutic applications. First I present our synthetic RNA-based technologies to control mammalian cell fate depending on cellular environment. We recently developed microRNA (miRNA)-responsive mRNAs (called “miRNA switch”) that detect the expression of endogenous miRNAs and identify target human cells. We applied the miRNA switch to purify various target cells derived from human pluripotent stem cells (hES/hiPS cells), including cardiomyocytes, hepatocytes, and insulin-producing cells. Synthetic RNA is safe because of low risk of random genomic integration. Second, I introduce the field of “molecular robotics” and possible future applications such as “molecular robots for human therapy”.

[ Profile ]

Oct.2014 – Present Professor, Center for iPS Cell Research and Application, Kyoto University
Jul.2011 – Sep.2014 Associate Professor, Center for iPS Cell Research and Application, Kyoto University
Apr.2010 – Sep.2014 Associate Professor, The HAKUBI Project, Kyoto University
Apr.2007–Mar.2012 Group Leader, Japan Science and Technology Agency(JST) ICORP, RNA Synthetic Biology Project
Oct. 2005–Mar.2010 Assistant, Graduate School of Bio Studies, Kyoto University Assistant Professor (from Apr.2007)
Apr.2005–Oct.2005 Researcher, Japan Science and Technology Agency(JST) CREST Cancer Institute of Japanese Foundation for Cancer Research
Apr.2002-Oct. 2005 JSPS Research Fellowship for Young Scientists(SPD) Cancer Institute of Japanese Foundation for Cancer Research
2002Ph.D Department of Chemistry and Biotechnology Graduate School of Engineering The University of Tokyo

Development of Nanomaterial-based Organic Thin-film
Photovoltaics for Self-Powered System 11:30-12:00
松本 英俊 氏

Hidetoshi Matsumoto
Associate Professor, Graduate School of Science and Engineering, Tokyo Institute of Technology

[ Abstract ]

Ambient energy harvesting technology is strongly required as self-powered system for maintenance-free mobile and wireless electronic devices. Among diverse nanomaterials, one-dimensional (1-D) nanomaterials such as nanofibers have unique properties compared to their bulk solids. In addition, they are easy to form a 2-D or 3-D network structure. This network structure enables an efficient charge transport through the network backbone and an efficient chemical reaction at the surface. Therefore, 1-D nanomaterials are promising for energy conversion and storage applications. This presentation provides our recent research works on nanofiber networks for energy harvesting and storage devices including polymer semiconductor networks for organic thin-film photovoltaics.

[ Profile ]

2002 Doctor of Engineering, Department of Organic and Polymeric Materials, Graduate School of Science and Engineering, Tokyo Institute of Technology. 2002 Assistant Professor, 2008 Associate Professor (special-appointment), and 2012 Associate Professor, Department of Organic and Polymeric Materials, Graduate School of Science and Engineering, Tokyo Institute of Technology.

Prospective view of the design of soft materials in the
point of view of simulation system 12:00-12:30

Hiroshi Morita
Team Leader, National Institute of Advanced Industrial Science and Technoloty (AIST)

[ Abstract ]

Since Materials genome initiative has proposed by president Obama at USA in 2011, the study of materials informatics (MI) has started growing in USA. Recently this trend also spread to Japan. NIMS with MEXT and METI also make the projects concerning with MI in this year, and now its wave becomes larger and larger. In the study of MI, the treatment of each information is one of the important issues and the software to control the information must become important tool for the study of MI. In this talk, we explain the simulation software system for soft materials, "OCTA," in which the simulators and the database of polymer are included. Along the function of OCTA and its expanded system, we will discuss the prospective view of material design based on the computational science.

[ Profile ]

Hiroshi Morita received a Doctor degree from Kyoto University in 1997. After graduate Kyoto University, he worked at JSR corporation until 2002. From 1998 to 2000, he temporary transferred to OCTA project in Nagoya university. In 2002, he studied at the university of Tokyo as a postdoctoral and worked with Prof. Toshio Nishi. From 2003, he studied as a postdoctoral position of JST and worked with Prof. Masao Doi. In 2008, he moved to AIST. Currently he belonged to research center for computational design center of advanced functional materials in AIST.

The potential of cellulose nanofibers
- Future automotive made from plant - 12:30-13:00
矢野 浩之 氏

Hiroyuki Yano
Professor, Kyoto University

[ Abstract ]

The plant cell wall consists of a cellulose nanofiber or a cellulose microfibril bundle. Since nanofibers are bundles of semi-crystalline extended cellulose chains, their thermal expansion is as low as that of quartz whilst their strength is five times that of steel. Recently, due to the risk of depletion of oil reserves and global environmental concern, the extraction of cellulose nanofibers and their utilizations has gained increasing attention. This lecture introduces the research works on the production of nanofibers from plant resources and their application in polymer composites for automotive parts.

[ Profile ]

Hiroyuki Yano is a Professor at the Research Institute of Sustainable Humanosphere, Kyoto University. He received his Ph.D. in wood science from Kyoto University. He received the Young Scientist Award from the Japan Wood Research Society in 1989, Hayashi Jisuke Award from the Cellulose Society of Japan in 2005, and the Japan Wood Research Society Award from the Japan Wood Research Society in 2009.


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